Dark Ones

The "Dark Ones" were a great race of evil beings evolved either from the snakes or the frogs, who have roamed the universe with the mission to destroy all other lifeforms. In its prior years, it had evolved into the Desert Muck Leech, which dwelt on Mars in a small puddle. They also evolved to have the power to read minds, communicate telepathicaly and suffocate people over long distances. They are also immune to mind reading (they probably don't have the Delta Brainwave like Fry

In their competition are the Encyclopods, whom tried to save all the endangered species that the Dark Ones threaten by storing their DNA. For a long time, the Encyclopods had been extinct, and the Dark Ones were thought to have won, but when the Chi redeveloped, and spawned new life in the violet dwarf system, the Dark Ones met their end when they destroyed by the new Encyclopod.

The Dark Ones nearly became extinct when Leo Wong built a parking lot over their living quarters on Mars for the new Mars Vegas, but Turanga Leela saved one of them. Before meeting its end, it managed to kill Frida Waterfall and her brother, Hutch Waterfall.

Trivia

 * They are momentarily disabled by the Omega Device.